High NA microscope objective lens designs span working distances of 0.3mm to 55mm, cover wavelengths from visible (390-750nm) to near infrared (700-1400nm) and can be modified for air, water, seawater, oil, and Focus Clear with housings of aluminum, stainless, ultem, Macor and titanium. Examples include: Infrared-optimized multiphoton objectives for imaging deep neuronal tissue sections, high transmission ~350 nm for laser microdissection, water, glycerol oil and multi-immersion for aberration=free imaging of thicker samples.