How Does Diffuse Optical Tomography Work?
Diffuse Optical Tomography (DOT) is a medical imaging technique that uses NIR light to measure the optical properties of translucent or semi-translucent biological tissue. That includes most soft tissue— breast and brain tissue, for instance, are good candidates for DOT.
Cellular scattering and variation in the tissue’s oxy and deoxy-hemoglobin concentrations, for example, can be imaged by recording spatial-temporal variations in light absorption as well as the scattering properties of tissue. Diffuse optical tomography is important for preclinical research, neurology, oncology, and surgery. It is sometimes known as near-infrared optical tomography or fluorescence diffuse optical tomography.