Advanced Microscope Objectives for Gene Sequencing, Biomedicine, and Semiconductor Inspection

July 3, 2025
2 min read

High-Throughput Microscope Objective for Gene Sequencing Instruments

A significant leap forward in life sciences, Avantier has developed a high-throughput microscope objective specifically designed for next-generation gene sequencing systems. Engineered for visible light imaging, the objective delivers a wide 2 mm field of view with a numerical aperture (NA) of 1.0, achieving diffraction-limited image quality across the field.

This advanced objective has already been adopted by a global leader in gene sequencing technology. Its integration has contributed directly to achieving the world’s highest daily throughput for gene sequencing, supporting fast, accurate, and scalable genomic analysis for both research and clinical applications.

Large Field-of-View, High-Resolution Microscope Objective

To address the growing need for wide-area, high-detail imaging in diagnostics and life sciences, Avantier developed a microscope objective that balances centimeter-level coverage with micron-level resolution.

Key specifications include:

  • Field of view: 10 mm

  • Resolution: as fine as 1.0 µm

  • Working distance: >25 mm

  • Spectral range: Visible to near-infrared

This objective is ideally suited for precision diagnostic systems, enabling clear, high-resolution imaging of large biological samples. Beyond healthcare, its design supports emerging applications in biomedicine, life sciences research, and machine vision—where both resolution and coverage are critical.

Developed in collaboration with a publicly listed semiconductor equipment manufacturer, the objective features:

  • Numerical aperture (NA): 0.9

  • Field of view: >1 mm

  • Spectral range: 355–500 nm

  • Wavefront aberration: <0.025λ

  • MTF: >0.25 at 3000 lp/mm

  • Physical resolution: better than 200 nm

To read the entire article, visit Avantier.

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